DOMIRE


DOMIRE is a web server for identifying structural domains and their neighbors in proteins

The DOMIRE web server implements a novel, automatic, protein structural domain assignment procedure based on 3D substructures of the query protein which are also found within structures of a non-redundant protein database. These common 3D substructures are transformed into a co-occurrence matrix that offers a global view of the protein domain organization. Three different algorithms are employed to define structural domain boundaries from this co-occurrence matrix. For each query, a list of structural neighbors and their alignments are provided. DOMIRE, by displaying the protein structural domain organization, can be a useful tool for defining protein common cores and for unravelling the evolutionary relationship between different proteins.


Informations générales
Partenaire externe
Mathematical and Statistical Computing Laboratory, Center for Information Technology and Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Suivi
Non-maintenu
Informations spécifiques
Langage(s) de développement
Langage(s) d'interface
N° de version courante
V1
OS supporté
Type de licence


Porteur(s)
Unité
MaIAGE
Equipe
StatInfOmics
Auteur(s)
Gibrat Jean-François
Contact
jean-francois.gibrat@inra.fr


 

 

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